SQUIRREL CHORUS - They sing, they dance, they chant, they comment. May double as STUDENTS, LITTLE TOMAS, LITTLE NANCY, CHIPMUNK, and LITLE GEORGIE.
TIPPY-TOE - Squirrel narrator. Doreen's best friend and crime-fighting partner.
DOREEN GREEN - a.k.a. Squirrel Girl. Our hero, college freshman, positive, enthusiatic, protective.
DOCTOR DOOM - Obsessive, humorless super villain.
TOMAS LARA-PEREZ - College freshman, former cheerleader, Doreen's crush.
NANCY WHITEHEAD - College freshman, Doreen's dorm roomate.
BRIGHTMIND - Luminous computer science professor. Doubles as GOOD TEACHER.
SMARTNOGGIN - Brightmind's offstage teaching assistant. Doubles as MEAN TEACHER.
FREAK - Freaky new teaching assistant.
MODOC - Suspicious substitute professor and super villain whose brain houses a giant computer.